Conceptual Organic Chemistry: Review of basic concepts of inductive effect, electromeric effect, resonance effect, hyperconjugation, the formalism of curved arrow mechanisms.
Relationship between thermodynamic stability and rates of reactions - kinetic versus thermodynamic control of product formation – Hammond postulate - kinetic isotope effects with examples - catalysis by acids and bases and nucleophiles with examples from acetal, cyanohydrin and ester formation and hydrolysis reactions - solvent effect, bulk and specific solvent effects - examples of solvent effect from SN2 substitution and E2 elimination reaction - introduction to carbon acids, pKa of weak acids. Concept of aromaticity, delocalization of electrons - Hückel‘s rule, criteria for aromaticity, examples of neutral and charged aromatic systems – annulenes - NMR as a tool for aromaticity - anti- and homo-aromatic systems. Mechanism of electrophilic and nucleophilic aromatic substitution reactions, with examples.
Stereochemistry: Introduction to
- Teacher: CH14B074 AKHIL T
- Teacher: Sekar G
- Teacher: pvenkat VENKATAKRISHNAN P