To familiarize the student with quantitative approaches for analyzing cellular metabolism and the use of theoretical and experimental tools that can give insights into the structure and regulation of metabolic networks. Using such insights, the cellular metabolic pathways can be re-engineered using genetic manipulation techniques, leading higher productivity, formation of new metabolic products or novel biotransformations. The course will also cover the ‘omics’ technologies for genomic, proteomic and metabolic analysis. Finally, case studies will be taken up on metabolically-engineered products and processes in various expression systems. Each of the following units will comprise of 6 - 8 lecture-hours.